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| Identity |
| 3D Structure |
| Physicochemical data |
| Environmental fate |
| Mammal toxicology |
| Ecotoxicology |
| Metabolism |
| Safety classifications |
| Evaluation |
Anthracene [120-12-7] |
| In mammals anthracene (1) is predominantly metabolized by cytochrome P450 to the 1,2-epoxide (2). The epoxide is hydrolyzed by epoxide hydrolase to give 1,2-dihydroanthracene-1,2-diol (3). In microorganisms this is only the first step for a total degradation of the ring system with many intermediates that ultimately lead to salicylic acid (10). Mammals excrete the 1,2-dihydroanthracene-1,2-diol (3) conjugated with sulfate or glucuronic acid in urine. In rats also 9,10-dihydroanthracene-9,10-diol (11) and anthracene-2,9,10-triol (12) have been shown to appear in urine as metabolites of anthracene (1). |
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