 |
| Identity |
| 3D Structure |
| Physicochemical data |
| Environmental fate |
| Mammal toxicology |
| Ecotoxicology |
| Metabolism |
| Safety classifications |
| Evaluation |
Cyclohexane [110-82-7] |
| Metabolisation of cyclohexane (1) in the mammalian organism involves mostly hydroxylated derivatives, which may be excreted in urine in free (2) or conjugated form (4). The first metabolite cyclohexanol (2) can be further oxidized by alcohol dehydrogeases to cyclohexanone (3). Cyclohexanone (3) can be metabolized by bacteria with opening of the ring to adipic acid (5). Cyclohexanol (2) or a metabolite thereof is toxic to spermatocytes and may cause kidney damage. |
 |