The classical variant of the "Isolation of trimyristin from nutmeg" is easily performed.
For an extraction of a product from natural sources the yield depends heavily on the
quality of the biological raw material and thus cannot be evaluated easily.
The purity of the product is very high.
Although (eco)toxicological data are not sufficient for an evaluation of educt and product,
acute or chronic toxicity cannot be reasonably expected, because the educt has been used as a spice
for hundreds of years and the product is usable as a foodstuff. The known toxicity of
nutmeg
is not based on its trimyristin content. Sufficient (eco)toxicological data are available for
the solvents used in extraction and recrystallization. The usual elution solvent in the
thin layer determination of trimyristin
n-hexane
has been replaced by
cyclohexane
which is not neurotoxic and has a similar polarity. The acute toxicity of educt, product
and the used solvents is relatively low
.
With the exception of the solvents
tert-butyl methyl ether
and
cyclohexane
which are biologically not easily degradable, all substances used or produced in the experiment
exhibit a low environmental persistence. Also the toxicity to aquatic organisms
is only low or medium.
Summed up we evaluate this experiment with an average economic efficiency
and low (eco)toxicological risks as well as a low environmental persistence for most of the substances
with the "green light".