Identity
3D Structure
Physicochemical data
Environmental fate
Mammal toxicology
Ecotoxicology
Metabolism
Safety classifications
Evaluation
Toluene [108-88-3]
Mammal toxicology
value
source
Lethal dose LD
50
50 mg/kg (oral) human (lowest lethal dose LD.Lo)
RTECS
Lethal dose LD
50
636 mg/kg (oral) rat
RTECS
Lethal dose LD
50
12200 mg/kg (dermal) rabbit
RTECS
Lethal concentration LC
50
49000 mg/m
3
(inhalation) rat
RTECS
Lethal concentration LC
50
20400 mg/m
3
(inhalation) mouse
RTECS
Toxic effects in humans
Slight irritation of the skin, headache, drowsiness
Merck MSDS
Carcinogenicity
not carcinogenic
TRGS 905
Mutagenicity
positive above 200 mg/kg not mutagenic (mouse) (micronucleus test)
RTECS
Mutation in microorganisms
not mutagenic (Salmonella typhimurium) (Ames test)
Merck MSDS
DNA repair
no data
Reproductive toxicity
reproductive toxicity only for high doses (rat)
RTECS
Sensitization
not sensitizing
WEKA
Neurotoxicity
no data
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pages/substance.php: November 09, 2022
views/mammal.php: November 09, 2022