 |
| Identity |
| 3D Structure |
| Physicochemical data |
| Environmental fate |
| Mammal toxicology |
| Ecotoxicology |
| Metabolism |
| Safety classifications |
| Evaluation |
2-Nitrotoluene [88-72-2] |
 |
Mammal toxicology
| value | source | ||
|---|---|---|---|
| Lethal dose LD50 | 970 mg/kg (oral) mouse | RTECS | |
| Lethal dose LD50 | 891 mg/kg (oral) rat | RTECS | |
| Lethal dose LD50 | 1750 mg/kg (oral) rabbit | RTECS | |
| Lethal concentration LC50 | 790 mg/m3 (inhalation) rat | RTECS | |
| Lethal concentration LC50 | 328 mg/m3 (inhalation) mouse | RTECS | |
| Toxic effects in humans | Methemoglobinemia, headache and cyanosis, aggravated by alcohol | Merck MSDS | |
| Carcinogenicity | positive above 353 mg/kg/d animal carcinogen (rat) | BAuA TRGS 905 | |
| Mutagenicity | positive above 150 mg/kg mutagenic (rat) (forming DNA adducts) | RTECS | |
| Mutagenicity | positive above 355 mg/kg mutagenic (hamster) (sister chromatid exchange) | RTECS | |
| Mutation in microorganisms | not mutagenic (Salmonella typhimurium) | BAuA TRGS 905 | |
| DNA repair | no data | ||
| Reproductive toxicity | suspected reproductive toxicity (rat) | BAuA TRGS 905 | |
| Sensitization | no data | ||
| Neurotoxicity | no data | ||