 |
| Identity |
| 3D Structure |
| Physicochemical data |
| Environmental fate |
| Mammal toxicology |
| Ecotoxicology |
| Metabolism |
| Safety classifications |
| Evaluation |
1,2-Ethanediol [107-21-1] |
 |
Mammal toxicology
| value | source | ||
|---|---|---|---|
| Lethal dose LD50 | 4700 to 5010 mg/kg (oral) rat | RTECS | |
| Lethal dose LD50 | 5500 mg/kg (oral) mouse | RTECS | |
| Lethal dose LD50 | 1650 mg/kg (oral) cat | RTECS | |
| Lethal dose LD50 | 10600 mg/kg (dermal) rabbit | RTECS | |
| Lethal concentration LC50 | 500 mg/m3 (inhalation) cat (or above (saturated atmosphere)) | RTECS | |
| Toxic effects in humans | In acute cases: kidney damage | BUA 92 | |
| Carcinogenicity | not carcinogenic (rat, mouse) | BUA 92 | |
| Mutagenicity | not mutagenic | BUA 92 | |
| Mutation in microorganisms | not mutagenic (Salmonella typhimurium) (Ames test) | BUA 92 | |
| DNA repair | positive above 60 mg/plate not mutagenic (Escherichia coli) | BUA 92 | |
| Reproductive toxicity | reproductive toxicity only for high doses | BUA 92 | |
| Sensitization | not sensitizing (calculated) | DEREK | |
| Neurotoxicity | no data | ||