 |
| Identity |
| 3D Structure |
| Physicochemical data |
| Environmental fate |
| Mammal toxicology |
| Ecotoxicology |
| Metabolism |
| Safety classifications |
| Evaluation |
4-Nitrotoluene [99-99-0] |
 |
Mammal toxicology
| value | source | ||
|---|---|---|---|
| Lethal dose LD50 | 1960 mg/kg (oral) rat | RTECS | |
| Lethal dose LD50 | ≥ 16000 mg/kg (dermal) rat | RTECS | |
| Lethal dose LD50 | 1230 mg/kg (oral) mouse | RTECS | |
| Lethal dose LD50 | 1750 mg/kg (oral) rabbit | ||
| Lethal concentration LC50 | 975 mg/m3 (inhalation) rat | ||
| Lethal concentration LC50 | 419 mg/m3 (inhalation) mouse | ||
| Toxic effects in humans | Methemoglobinemia, headache and cyanosis | Merck MSDS | |
| Carcinogenicity | suspected carcinogen (calculated) | DEREK | |
| Mutagenicity | positive above 200 mg/L mutagenic (hamster) (sister chromatid exchange) | RTECS | |
| Mutation in microorganisms | positive above 10 µg/plate mutagenic (Salmonella typhimurium) (Ames test) | RTECS | |
| DNA repair | positive above 5 mg/disc mutagenic (Bacillus subtilis) | RTECS | |
| Reproductive toxicity | no reproductive toxicity (calculated) | TOPKAT | |
| Sensitization | no data | ||
| Neurotoxicity | no data | ||