Theoretical prediction: In mammals metabolisation of 2-(3-nitrophenyl)-1,3-dioxolane (1) may proceed with hydroxylation of the aromatic ring or hydroxylation of the dioxolane ring by cytochrome P450. Metabolites hydroxylated in the dioxolane ring will decompose in several steps non-enzymatically to hydroxyacetaldehyde (2) and 3-nitrobenzaldehyde (3), both products may be further oxidized by alcohol dehydrogenase respectively aldehyde dehydrogenase to yield 3-nitrobenzoic acid (4) and glycolic acid (5). Metabolites hydroxylated in the aromatic ring (6) may subsequently be conjugated with glucuronic acid or sulfate and excreted in urine. A reduction of the nitro group by the gut flora may be another possible metabolic pathway.
Further degradation of 3-nitrobenzaldehyde (3) see on metabolism page of 3-nitrobenzaldehyde.