 |
| Identity |
| 3D Structure |
| Physicochemical data |
| Environmental fate |
| Mammal toxicology |
| Ecotoxicology |
| Metabolism |
| Safety classifications |
| Evaluation |
2,4-Dinitrotoluene [121-14-2] |
 |
Mammal toxicology
| value | source | ||
|---|---|---|---|
| Lethal dose LD50 | 268 mg/kg (oral) rat | RTECS | |
| Lethal dose LD50 | 790 mg/kg (oral) mouse | RTECS | |
| Lethal dose LD50 | ≥ 1000 mg/kg (dermal) guinea pig | RTECS | |
| Lethal concentration LC50 | no data | ||
| Toxic effects in humans | Methemoglobinemia, headache and cyanosis | WEKA | |
| Carcinogenicity | animal carcinogen (rat) | RTECS | |
| Carcinogenicity | animal carcinogen (mouse) | RTECS | |
| Mutagenicity | positive above 10 mg/kg mutagenic (rat) (forming DNA adducts) | RTECS | |
| Mutagenicity | positive above 1010 mg/L weakly mutagenic (hamster) (sister chromatid exchange) | RTECS | |
| Mutagenicity | positive above 200 mg/L mutagenic (mouse) (lymphocyte assay) | RTECS | |
| Mutation in microorganisms | positive above 10 µg/plate mutagenic (Salmonella typhimurium) (Ames test) | RTECS | |
| DNA repair | no data | ||
| Reproductive toxicity | evidence of reproductive toxicity (rat) | RTECS | |
| Sensitization | no data | ||
| Neurotoxicity | no data | ||