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3D Structure
Physicochemical data
Environmental fate
Mammal toxicology
Ecotoxicology
Metabolism
Safety classifications
Evaluation
Dichloromethane [75-09-2]
Mammal toxicology
value
source
Lethal dose LD
50
1600 mg/kg (oral) rat
RTECS
Lethal dose LD
50
873 mg/kg (oral) mouse
RTECS
Lethal concentration LC
50
88000 mg/m
3
(inhalation) rat
RTECS
Lethal concentration LC
50
52000 mg/m
3
(inhalation) rat
RTECS
Toxic effects in humans
Irritatrion of the mucous membranes, narcosis, toxic effects on liver and kidneys
Merck MSDS
Carcinogenicity
positive above 3500 ppm animal carcinogen (rat)
RTECS
Carcinogenicity
positive above 2000 ppm animal carcinogen (mouse)
RTECS
Mutagenicity
not mutagenic (mouse) (lymphocyte assay)
BUA 6
Mutagenicity
not mutagenic (mouse) (micronucleus test)
BUA 6
Mutagenicity
positive above 13.9 mg/L mutagenic (mouse) (sister chromatid exchange)
RTECS
Mutation in microorganisms
positive above 5700 ppm weakly mutagenic (Salmonella typhimurium) (Ames test)
RTECS
DNA repair
no data
Reproductive toxicity
no reproductive toxicity (rat)
BUA 6
Sensitization
not sensitizing
Merck MSDS
Neurotoxicity
no data
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pages/substance.php: November 09, 2022
views/mammal.php: November 09, 2022