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3D Structure
Physicochemical data
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Mammal toxicology
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Evaluation
2-Nitrotolueno [88-72-2]
Mammal toxicology
value
source
Lethal dose LD
50
970 mg/kg (oral) mouse
RTECS
Lethal dose LD
50
891 mg/kg (oral) rat
RTECS
Lethal dose LD
50
1750 mg/kg (oral) rabbit
RTECS
Lethal concentration LC
50
790 mg/m
3
(inhalation) rat
RTECS
Lethal concentration LC
50
328 mg/m
3
(inhalation) mouse
RTECS
Toxic effects in humans
Metahemoglobinemia, dolor de cabeza y cianosis, agravado por alcohol
Merck MSDS
Carcinogenicity
positive above 353 mg/kg/d animal carcinogen (rat)
BAuA TRGS 905
Mutagenicity
positive above 150 mg/kg mutagenic (rat) (forming DNA adducts)
RTECS
Mutagenicity
positive above 355 mg/kg mutagenic (hamster) (sister chromatid exchange)
RTECS
Mutation in microorganisms
not mutagenic (Salmonella typhimurium)
BAuA TRGS 905
DNA repair
no data
Reproductive toxicity
suspected reproductive toxicity (rat)
BAuA TRGS 905
Sensitization
no data
Neurotoxicity
no data
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pages/substance.php: 09 Nov 2022
views/mammal.php: 09 Nov 2022