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3D Structure
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Mammal toxicology
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Evaluation
n-Hexano [110-54-3]
Mammal toxicology
value
source
Lethal dose LD
50
25000 mg/kg (oral) rat
RTECS
Lethal dose LD
50
28700 mg/kg (oral) rat
Merck MSDS
Lethal dose LD
50
≥ 2000 mg/kg (dermal) rabbit
Merck MSDS
Lethal concentration LC
50
172000 mg/m
3
(inhalation) rat
Merck MSDS
Lethal concentration LC
50
120000 mg/m
3
(inhalation) mouse
Merck MSDS
Toxic effects in humans
no data
Carcinogenicity
positive above 32300 mg/m^3 suspected carcinogen only for high inhalative doses (mouse)
RTECS
Carcinogenicity
not carcinogenic (rat)
DFG-MAK-Begründungen
Mutagenicity
no data
Mutation in microorganisms
not mutagenic (Salmonella typhimurium) (Ames test)
Merck MSDS
DNA repair
no data
Reproductive toxicity
suspected reproductive toxicity
Merck MSDS
Sensitization
not sensitizing (human)
DFG-MAK-Begründungen
Neurotoxicity
positive above 1790 mg/m^3 neurotoxic (rat) ((9 weeks, spastic paralysis))
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pages/substance.php: 09 Nov 2022
views/mammal.php: 09 Nov 2022