NOP - Sustainability in the organic chemistry lab course

Anisole

+

Acetic anhydride

Sc(OTf)₃

reacts to

p-Methoxyacetophenone

+

Acetic acid

; Side reactions

¹H-NMR

1H NMR

¹H-NMR: crude product
400 MHz, CDCl₃, TMS
delta [ppm]	mult.	atoms	assignment
2.55	s	3 H	-C(=O)-CH₃
3.86	s	3 H	-OCH₃
6.91-6.95	m (AA')	2 H	3-H
7.91-7.95	m (XX')	2 H	2-H
2.09	s		CH₃ (acetic acid)
3.78	s		-OCH₃ (educt anisole)
4.28	s		CH₃ (nitromethanr)

1H NMR

¹H-NMR: p-Methoxyacetophenone
400 MHz, CDCl₃, TMS
delta [ppm]	mult.	atoms	assignment
2.55	s	3 H	-C(=O)-CH₃
3.86	s	3 H	-OCH₃
6.91-6.95	m (AA')	2 H	3-H
7.91-7.95	m (XX')	2 H	2-H
2.09	s		CH₃ (acetic acid)
3.78	s		-OCH₃ (educt anisole)
4.28	s		CH₃ (nitromethanr)